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G protein-gated inwardly rectifying potassium (GIRK) channels hyperpolarize neurons in response to activation girkof many different G protein-coupled receptors and thus control the...

G protein-coupled inwardly rectifying potassgirkium (GIRK) channels can be activated or inhibited by different classes of receptors, suggesting a role for G proteins in determining signaling specificity.

The G protein-coupled inwardly rectifying potassium channels (GIRKs) are a family of lipid-gated inward-rectifier potassium ion channels which are activated (opened) by the signaling lipid PIP2 and a signal transduction cascade starting with ligand -stimulated G protein-coupled receptors (GPCRs). [1][2] GPCRs in turn release activated G-protein ...

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girk|G protein

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Emerging roles for G protein Emerging roles for G protein
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girk|G protein

girk|G protein

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Structural Insights into GIRK Channel Function Structural Insights into GIRK Channel Function Structural Insights into GIRK Channel Function Structural Insights into GIRK Channel Function Structural Insights into GIRK Channel Function
Structural insights into GIRK2 channel modulation by cholesterol。 Structural insights into GIRK2 channel modulation by cholesterol。 Structural insights into GIRK2 channel modulation by cholesterol。 Structural insights into GIRK2 channel modulation by cholesterol。 Structural insights into GIRK2 channel modulation by cholesterol。
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Structural mechanism underlying G protein family Structural mechanism underlying G protein family Structural mechanism underlying G protein family Structural mechanism underlying G protein family Structural mechanism underlying G protein family
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